2. Immunology/Inflammation Metabolic Enzyme/Protease
  3. PSMA Carboxypeptidase
  4. GCPII-IN-1 TFA

GCPII-IN-1 (Compound 2) TFA is a GCPII (also known as PSMA) inhibitor with a Ki of 44.3 nM. GCPII-IN-1 TFA can be used in the research of prostate cancer.

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GCPII-IN-1 TFA

GCPII-IN-1 TFA 화학구조

CAS No. : 1269794-89-9

사이즈 가격 재고 수량
5 mg 해외재고보유
10 mg 해외재고보유
50 mg   견적 받기  
100 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of GCPII-IN-1 TFA:

GCPII-IN-1 TFA Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

GCPII-IN-1 (Compound 2) TFA is a GCPII (also known as PSMA) inhibitor with a Ki of 44.3 nM. GCPII-IN-1 TFA can be used in the research of prostate cancer[1].

In Vitro

GCPII-IN-1 (compound KUE) TFA serves as a PSMA targeting vector to be conjugated with the zwitterionic metal chelators to generate probes for prostate cancer imaging applications[2].
GCPII-IN-1 TFA can be radiolabeled with F-18 to be a PET agent for prostate cancer imaging[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

GCPII-IN-1 TFA Related Antibodies
분자량

433.33

화학식

C14H22F3N3O9
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(C(F)(F)F)=O.NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

용액&용해도
In Vitro: 

H2O : 160 mg/mL (369.23 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3077 mL 11.5386 mL 23.0771 mL
5 mM 0.4615 mL 2.3077 mL 4.6154 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 25 mg/mL (57.69 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서

Purity: 99.58%

SDS (393 KB)

COA (248 KB) HNMR (167 KB) LCMS (91 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.3077 mL 11.5386 mL 23.0771 mL 57.6928 mL
5 mM 0.4615 mL 2.3077 mL 4.6154 mL 11.5386 mL
10 mM 0.2308 mL 1.1539 mL 2.3077 mL 5.7693 mL
15 mM 0.1538 mL 0.7692 mL 1.5385 mL 3.8462 mL
20 mM 0.1154 mL 0.5769 mL 1.1539 mL 2.8846 mL
25 mM 0.0923 mL 0.4615 mL 0.9231 mL 2.3077 mL
30 mM 0.0769 mL 0.3846 mL 0.7692 mL 1.9231 mL
40 mM 0.0577 mL 0.2885 mL 0.5769 mL 1.4423 mL
50 mM 0.0462 mL 0.2308 mL 0.4615 mL 1.1539 mL
60 mM 0.0385 mL 0.1923 mL 0.3846 mL 0.9615 mL
80 mM 0.0288 mL 0.1442 mL 0.2885 mL 0.7212 mL
100 mM 0.0231 mL 0.1154 mL 0.2308 mL 0.5769 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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GCPII-IN-1 TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GCPII-IN-11269794-89-9PSMACarboxypeptidaseProstate-specific membrane antigenGCPIIscaffoldInhibitorinhibitorinhibit

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상품명:
GCPII-IN-1 TFA
Cat. No.:
HY-139840A
수량:
MCE Japan Authorized Agent:

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SAFETY DATA SHEET (SDS)

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