Fosb - FosB proto-oncogene, AP-1 transcription factor subunit Gene

Also Known as fra-2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 100360880

Summary

Enables DNA-binding transcription factor activity; double-stranded DNA binding activity; and sequence-specific DNA binding activity. Involved in several processes, including response to cAMP; response to morphine; and response to steroid hormone. Located in nucleus. Orthologous to human FOSB (FosB proto-oncogene, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, Apr 2022]

Fosb Products (1)

mRNA Protein Name
NM_001256509.1 NP_001243438.1 protein FosB

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IMP
IMP: Inferred from mutant phenotype
10830307 RGD
enables double-stranded DNA binding IDA
IDA: Inferred from direct assay
10830307 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
10830307 RGD
Biological Process GO Annotation Evidence References Source
involved in behavioral response to cocaine IEP
IEP: Inferred from expression pattern
20633205 RGD
involved in cellular response to hormone stimulus IEP
IEP: Inferred from expression pattern
11460264 RGD
involved in female pregnancy IEP
IEP: Inferred from expression pattern
12080023 RGD
involved in response to amphetamine IEP
IEP: Inferred from expression pattern
31373119 RGD
involved in response to cAMP IEP
IEP: Inferred from expression pattern
10934195 RGD
involved in response to cocaine IEP
IEP: Inferred from expression pattern
17572394 RGD
involved in response to corticosterone IEP
IEP: Inferred from expression pattern
18485334 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
19324071 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
15126239 RGD
involved in response to morphine IEP
IEP: Inferred from expression pattern
20438612 RGD
involved in response to progesterone IEP
IEP: Inferred from expression pattern
11750070 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
12093589 RGD
involved in transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
10830307 RGD
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
20438612 RGD
located in nucleus IDA
IDA: Inferred from direct assay
17572394 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein FosB

protein fosB

  • FBJ osteosarcoma oncogene B

  • transcription factor AP-1 subunit FosB

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-179594 HTS10307 Inhibitor / Unkown
HY-W471288 JPC0661 Inhibitor / Unkown
HY-170916 Angiogenesis inhibitor 7 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fosb NCBI NCBI:2354