Card11 - caspase recruitment domain family, member 11 Gene

Predicted to enable CARD domain binding activity and protein self-association. Predicted to be involved in several processes, including intracellular signal transduction; positive regulation of NF-kappaB transcription factor activity; and positive regulation of T cell receptor signaling pathway. Predicted to act upstream of or within several processes, including lymphocyte differentiation; positive regulation of interleukin-2 production; and regulation of lymphocyte activation. Predicted to be located in cytoplasm; immunological synapse; and membrane raft. Predicted to be part of CBM complex. Human ortholog(s) of this gene implicated in diffuse large B-cell lymphoma; immunodeficiency 11A; and immunodeficiency 11B. Orthologous to human CARD11 (Caspase recruitment domain family member 11). [provided by Alliance of Genome Resources, Apr 2022]