1. Metabolic Enzyme/Protease NF-κB
  2. MALT1
  3. MLT-985

MLT-985 is a highly selective allosteric MALT1 inhibitor with an IC50 value of 3 nM.

For research use only. We do not sell to patients.

MLT-985 Chemical Structure

MLT-985 Chemical Structure

CAS No. : 1832576-25-6

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 418 In-stock
Solution
10 mM * 1 mL in DMSO USD 418 In-stock
Solid
5 mg USD 380 In-stock
10 mg USD 620 In-stock
25 mg USD 1250 In-stock
50 mg USD 2000 In-stock
100 mg USD 3200 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of MLT-985:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

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Description

MLT-985 is a highly selective allosteric MALT1 inhibitor with an IC50 value of 3 nM.

Molecular Weight

448.27

Formula

C17H15Cl2N9O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CO[C@H](C1=C(NC(NC2=CN=C(N3N=CC=N3)C(Cl)=C2)=O)C=NC4=CC(Cl)=NN14)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (223.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2308 mL 11.1540 mL 22.3080 mL
5 mM 0.4462 mL 2.2308 mL 4.4616 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2308 mL 11.1540 mL 22.3080 mL 55.7700 mL
5 mM 0.4462 mL 2.2308 mL 4.4616 mL 11.1540 mL
10 mM 0.2231 mL 1.1154 mL 2.2308 mL 5.5770 mL
15 mM 0.1487 mL 0.7436 mL 1.4872 mL 3.7180 mL
20 mM 0.1115 mL 0.5577 mL 1.1154 mL 2.7885 mL
25 mM 0.0892 mL 0.4462 mL 0.8923 mL 2.2308 mL
30 mM 0.0744 mL 0.3718 mL 0.7436 mL 1.8590 mL
40 mM 0.0558 mL 0.2788 mL 0.5577 mL 1.3942 mL
50 mM 0.0446 mL 0.2231 mL 0.4462 mL 1.1154 mL
60 mM 0.0372 mL 0.1859 mL 0.3718 mL 0.9295 mL
80 mM 0.0279 mL 0.1394 mL 0.2788 mL 0.6971 mL
100 mM 0.0223 mL 0.1115 mL 0.2231 mL 0.5577 mL
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MLT-985 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
MLT-985
Cat. No.:
HY-142648
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