Cdc37 - cell division cycle 37, HSP90 cochaperone Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114562

Summary

Enables chaperone binding activity; protein C-terminus binding activity; and protein kinase binding activity. Involved in regulation of cell cycle. Located in cytoplasm and ruffle membrane. Part of protein-containing complex. Orthologous to human CDC37 (cell division cycle 37, HSP90 cochaperone). [provided by Alliance of Genome Resources, Apr 2022]

Cdc37 Products (1)

mRNA Protein Name
NM_053743.2 NP_446195.2 hsp90 co-chaperone Cdc37

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables mitogen-activated protein kinase kinase kinase binding IPI
IPI: Inferred from physical interaction
16335536 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
23428871 RGD
enables protein kinase B binding IPI
IPI: Inferred from physical interaction
16335536 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
16335536 RGD
enables protein-folding chaperone binding IPI
IPI: Inferred from physical interaction
16335536 RGD
enables transcription corepressor binding IPI
IPI: Inferred from physical interaction
8945638 RGD
Cellular Component GO Annotation Evidence References Source
part of protein-containing complex IDA
IDA: Inferred from direct assay
16335536 RGD
located in ruffle membrane IDA
IDA: Inferred from direct assay
16335536 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hsp90 co-chaperone Cdc37

  • CDC37 (cell division cycle 37 S. cerevisiae homolog)

  • cell division cycle 37 homolog

  • hsp90 chaperone protein kinase-targeting subunit

  • p50Cdc37

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-139301 DDO-5936 Inhibitor 98.33% Unkown
HY-N1986 Cucurbitacin D 99.93% Unkown
HY-144650 Hsp90-Cdc37-IN-3 98.09% Unkown
HY-119906 Conglobatin 95.48% Unkown
HY-169947 DDO-6079 Inhibitor 98.92% Unkown
HY-111414 Hsp90-Cdc37-IN-1 Inhibitor 99.66% Unkown
HY-147125 DDO-6600 99.2% Unkown
HY-N3417 Kongensin A 98.0% Unkown
HY-130624 Hsp90-Cdc37-IN-2 / Unkown
HY-174347 Hsp90-Cdc37-IN-4 / Unkown
HY-RS02297 CDC37 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02298 CDC37L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17502 Cdc37 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23959 Cdc37 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdc37 NCBI NCBI:11140