2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. HSP
  4. Hsp90-Cdc37-IN-1

Hsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptor that inhibit cell migration and reverse agent resistance, with an IC50 of 140 nM.

For research use only. We do not sell to patients.

Hsp90-Cdc37-IN-1 Chemical Structure

Hsp90-Cdc37-IN-1 Chemical Structure

CAS No. : 2227303-22-0

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5 mg USD 180 In-stock
10 mg USD 290 In-stock
25 mg USD 580 In-stock
50 mg USD 920 In-stock
100 mg USD 1450 In-stock
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Based on 1 publication(s) in Google Scholar

Hsp90-Cdc37-IN-1 Related Antibodies

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Description

Hsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptor that inhibit cell migration and reverse agent resistance, with an IC50 of 140 nM.

IC50 & Target

IC50: 140 nM (Hsp90-Cdc37)[1]
Molecular Weight

748.99

Formula

C43H57FN2O6S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]1(C(OCC)=O)C[C@]2([H])[C@](CC[C@]([C@@]3(C)[C@@]4([H])[C@]5(C)[C@@](C(C)(C)[C@@H](OC(CCC(NC6=NC7=C(C=C(F)C=C7)S6)=O)=O)CC5)([H])CC3)(C)C2=CC4=O)(C)CC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 2.86 mg/mL (3.82 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3351 mL 6.6757 mL 13.3513 mL
5 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3351 mL 6.6757 mL 13.3513 mL 33.3783 mL
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Hsp90-Cdc37-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hsp90-Cdc37-IN-12227303-22-0HSPHeat shock proteinsInhibitorinhibitorinhibit

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