Pfkfb3 - 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117276

Summary

Predicted to enable 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Involved in brain development and fructose 2,6-bisphosphate metabolic process. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Orthologous to human PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3). [provided by Alliance of Genome Resources, Apr 2022]

Pfkfb3 Products (1)

mRNA Protein Name
NM_057135.1 NP_476476.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in fructose 2,6-bisphosphate metabolic process IDA
IDA: Inferred from direct assay
17553851 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

  • 6PF-2-K/Fru-2,6-P2ASE brain-type isozyme

  • 6PF-2-K/Fru-2,6-P2ase 3

  • PFK/FBPase 3

  • RB2K

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-12203 PFK-158 Inducer 98.95% Phase 1

Pre-clinical Phase

Bioactive Molecules (15)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-19824 3PO Inhibitor 99.85% Unkown
HY-12204 PFK-015 Inhibitor 99.48% Unkown
HY-101972 AZ-PFKFB3-67 Inhibitor 97.03% Unkown
HY-123981 5MPN 99.89% Unkown
HY-101971 AZ PFKFB3 26 Inhibitor 99.23% Unkown
HY-112808 KAN0438757 Inhibitor 99.41% Unkown
HY-110156 YZ9 Inhibitor 98.89% Unkown
HY-153077 PFKFB3-IN-2 Inhibitor 99.86% Unkown
HY-178367 PFKFB4-IN-1 99.91% Unkown
HY-RS10363 PFKFB3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-101972A AZ-PFKFB3-67 quarterhydrate Inhibitor 99.0% Unkown
HY-184148 PFKFB3-IN-3 Inhibitor / Unkown
HY-110169 (E/Z)-3PO Inhibitor 99.86% Unkown
HY-RS16558 Pfkfb3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22990 Pfkfb3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pfkfb3 NCBI NCBI:5209