2. Metabolic Enzyme/Protease
  3. Phosphatase
  4. PFKFB3-IN-2

PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor. PFKFB3-IN-2 has potential applications in cancer, neurodegenerative diseases, autoimmune diseases, inflammatory diseases, multiple sclerosis, metabolic diseases, angiogenesis inhibition and other diseases.

For research use only. We do not sell to patients.

PFKFB3-IN-2 Chemical Structure

PFKFB3-IN-2 Chemical Structure

CAS No. : 794552-84-4

Size Price Stock Quantity
1 mg USD 66 In-stock
5 mg USD 200 In-stock
10 mg USD 320 In-stock
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Based on 1 publication(s) in Google Scholar

PFKFB3-IN-2 Related Antibodies

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Description

PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor. PFKFB3-IN-2 has potential applications in cancer, neurodegenerative diseases, autoimmune diseases, inflammatory diseases, multiple sclerosis, metabolic diseases, angiogenesis inhibition and other diseases[1].

Molecular Weight

337.30

Formula

C14H11NO7S
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

O=C(C1=CC=CC(S(=O)(NC2=CC=C(C(O)=C2)C(O)=O)=O)=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (370.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9647 mL 14.8236 mL 29.6472 mL
5 mM 0.5929 mL 2.9647 mL 5.9294 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.53%

COA (248 KB) HNMR (271 KB) LCMS (97 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9647 mL 14.8236 mL 29.6472 mL 74.1180 mL
5 mM 0.5929 mL 2.9647 mL 5.9294 mL 14.8236 mL
10 mM 0.2965 mL 1.4824 mL 2.9647 mL 7.4118 mL
15 mM 0.1976 mL 0.9882 mL 1.9765 mL 4.9412 mL
20 mM 0.1482 mL 0.7412 mL 1.4824 mL 3.7059 mL
25 mM 0.1186 mL 0.5929 mL 1.1859 mL 2.9647 mL
30 mM 0.0988 mL 0.4941 mL 0.9882 mL 2.4706 mL
40 mM 0.0741 mL 0.3706 mL 0.7412 mL 1.8529 mL
50 mM 0.0593 mL 0.2965 mL 0.5929 mL 1.4824 mL
60 mM 0.0494 mL 0.2471 mL 0.4941 mL 1.2353 mL
80 mM 0.0371 mL 0.1853 mL 0.3706 mL 0.9265 mL
100 mM 0.0296 mL 0.1482 mL 0.2965 mL 0.7412 mL
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PFKFB3-IN-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PFKFB3-IN-2794552-84-4PhosphatasePFKFB3Inhibitorinhibitorinhibit

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