Cd34 - CD34 antigen Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12490

Summary

Enables sulfate binding activity. Acts upstream of or within leukocyte migration. Located in cytoplasm; external side of plasma membrane; and extracellular region. Is expressed in several structures, including alimentary system; cardiovascular system; extraembryonic component; genitourinary system; and skin. Orthologous to human CD34 (CD34 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd34 Products (2)

mRNA Protein Name
NM_001111059.2 NP_001104529.1 hematopoietic progenitor cell antigen CD34 isoform 1 precursor
NM_133654.4 NP_598415.1 hematopoietic progenitor cell antigen CD34 isoform 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables sulfate binding IDA
IDA: Inferred from direct assay
14597732 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within leukocyte migration IMP
IMP: Inferred from mutant phenotype
15701716 MGI
Cellular Component GO Annotation Evidence References Source
located in cell periphery IDA
IDA: Inferred from direct assay
21464233 MGI
located in cell surface IDA
IDA: Inferred from direct assay
9324354 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
17717145 MGI
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
10943842 MGI
located in extracellular region IDA
IDA: Inferred from direct assay
14597732 MGI
located in membrane IDA
IDA: Inferred from direct assay
17717145 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hematopoietic progenitor cell antigen CD34

  • cluster designation 34

Recombinant Cd34 Proteins

Cat. No. Product Name Accession Purity
HY-P74305 CD34 Protein, Mouse (HEK293, His) Q64314 (T35-T287) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15306 Eltrombopag 99.94% Yes
HY-15306A Eltrombopag Olamine 99.96% Yes

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-19867A Burixafor hydrobromide Antagonist 99.70% Phase 2
HY-19867 Burixafor Antagonist / Phase 2
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Phase
HY-P990351 Anti-CD34 Antibody Inhibitor 99.90% Phase 4
HY-P991329 ASP-1948 Inhibitor / Phase 1
HY-P991419 MSB-0254 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-NP199 Bovine pituitary extract Modulator / Unkown
HY-170823 PRC1-IN-1 Inhibitor 97.30% Unkown
HY-150109A Purinostat Inhibitor 98.04% Unkown
HY-106784 Ajoene ≥99.0% Unkown
HY-110208 BRD9876 99.37% Unkown
HY-124693 DB1055 Inducer 99.68% Unkown
HY-108417 Debio 0617B Inhibitor / Unkown
HY-125090 PHA-680626 / Unkown
HY-15001A Stemregenin 1 hydrochloride Antagonist / Unkown
HY-150239 BAY-364 Inhibitor / Unkown
HY-RS02236 CD34 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16784 Cd34 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23224 Cd34 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990352 Anti-CD36 Antibody Inhibitor 99.43% Unkown
HY-P990274 Anti-Canine CD34 Antibody (1H6) / Unkown
HY-P991328 MAb604.107 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd34 NCBI NCBI:947