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ZFP3 - ZFP3 zinc finger protein Gene

Also Known as ZNF752

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 124961

About ZFP3

Cytogenetic location: 17p13.2 Genomic coordinates (GRCh38): 17:5,078,467-5,096,374 (from NCBI)

This gene has 1 transcript (splice variant), 80 orthologues and 174 paralogues. Ubiquitous expression in thyroid (RPKM 4.0), duodenum (RPKM 3.8) and 24 other tissues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZFP3 Products (1)

mRNA	Protein	Name
NM_153018.3	NP_694563.1	zinc finger protein 3 homolog

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZFP3 Protein Structure

zf-H2C2_2

0
100
200
300
400
502 a.a.

Protein Preferred Names	Protein Names
zinc finger protein 3 homolog	zfp-3

ZFP3 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	ZFP3	Q96NJ6	YJU2B	Homo sapiens	P13994	Y2H Array	32296183
Intra	ZFP3	Q96NJ6	YJU2B	Homo sapiens	P13994	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Sleeping Sickness	African Trypanosomiasis African Sleeping Sickness Trypanosomiasis, Human East-African Trypanosomiasis, East African Trypanosomiasis African Trypanosomiasis, African Human African Trypanosomiasis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16039	ZFP3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	ZFP3	VGNC	VGNC:37161
Canis familiaris	ZFP3	VGNC	VGNC:48610
Mus musculus	ZFP3	MGD	MGI:99177
Rattus norvegicus	ZFP3	RGD	RGD:1565881
Others	ZFP3	NCBI