Cyp7a1 - cytochrome P450, family 7, subfamily a, polypeptide 1 Gene

Also Known as CYPVII; CYPVIIc

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13122

Summary

Enables Cholesterol 7-alpha-monooxygenase activity. Acts upstream of or within Cholesterol catabolic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in liver. Orthologous to human CYP7A1 (Cytochrome P450 family 7 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp7a1 Products (1)

mRNA Protein Name
NM_007824.3 NP_031850.2 cytochrome P450 7A1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables cholesterol 7-alpha-monooxygenase activity IDA
IDA: Inferred from direct assay
11279518 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cholesterol catabolic process IDA
IDA: Inferred from direct assay
11279518 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome P450 7A1

  • 24-hydroxycholesterol 7-alpha-hydroxylase

  • cholesterol 7-alpha-hydroxylase

  • cholesterol 7-alpha-monooxygenase

  • cytochrome P450, 7a1

Cyp7a1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P81069 CYP7A1 Antibody WB Human, Mouse

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-106539 Colesevelam hydrochloride 98.00% Unkown

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-19264 264W94 / Phase 2

Pre-clinical Phase

Bioactive Molecules (17)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W008226 Phloracetophenone 99.96% Unkown
HY-113259 7α-Hydroxy-4-cholesten-3-one 99.60% Unkown
HY-163436 F44-A13 96.73% Unkown
HY-N0430A Coptisine Sulfate 99.37% Unkown
HY-117147A GSK2945 hydrochloride 98.49% Unkown
HY-117147 GSK2945 Activator / Unkown
HY-175266 MI1013 99.10% Unkown
HY-N0430 Coptisine / Unkown
HY-RS03487 CYP7A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-181761 FXR agonist 16 Agonist / Unkown
HY-RS03488 CYP7B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174703 Human FGF19 mRNA / Unkown
HY-N13218 Pueraria Extract / Unkown
HY-RS17211 Cyp7a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18706 Cyp7b1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23663 Cyp7a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25193 Cyp7b1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cyp7a1 NCBI NCBI:1581