Edar - ectodysplasin-A receptor Gene
Also Known as dl; ED3; ED5; ED1R; EDA3; EDA-A1R
Species: Mus musculus
Summary
Predicted to enable transmembrane signaling receptor activity. Acts upstream of or within several processes, including animal organ development; positive regulation of NIK/NF-kappaB signaling; and positive regulation of gene expression. Located in apical part of cell and plasma membrane. Is expressed in several structures, including embryo ectoderm; integumental system; male accessory gland; oral region epithelium; and tooth. Used to study hypohidrotic ectodermal dysplasia. Human ortholog(s) of this gene implicated in ectodermal dysplasia 10A and ectodermal dysplasia 10B. Orthologous to human EDAR (ectodysplasin A receptor). [provided by Alliance of Genome Resources, Apr 2022]
Edar Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_010100.3 | NP_034230.1 | tumor necrosis factor receptor superfamily member EDAR precursor |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
tumor necrosis factor receptor superfamily member EDAR |
|
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Recombinant Edar Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P70115 | EDAR Protein, Mouse (HEK293, Fc) | Q9R187 (E27-I189) | ≥ 95%, as determined by reducing SDS-PAGE. |