Eif4a2 - eukaryotic translation initiation factor 4A2 Gene

Also Known as Eif4; Ddx2b; BM-010; eIF4A-II; eIF-4A-II; 4833432N07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13682

Summary

Predicted to enable ATP hydrolysis activity and translation initiation factor activity. Acts upstream of or within cellular response to Leukemia Inhibitory Factor. Predicted to be located in perinuclear region of cytoplasm. Is expressed in brain; early conceptus; oocyte; and telencephalon. Orthologous to human EIF4A2 (eukaryotic translation initiation factor 4A2). [provided by Alliance of Genome Resources, Apr 2022]

Eif4a2 Products (4)

mRNA Protein Name
NM_001123037.2 NP_001116509.1 eukaryotic initiation factor 4A-II isoform b
NM_001123038.2 NP_001116510.1 eukaryotic initiation factor 4A-II isoform c
NM_001347179.2 NP_001334108.1 eukaryotic initiation factor 4A-II isoform d
NM_013506.3 NP_038534.2 eukaryotic initiation factor 4A-II isoform a

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eukaryotic initiation factor 4A-II

  • ATP-dependent RNA helicase eIF4A-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-145262 eIF4E-IN-2 Inhibitor 98.91% Unkown
HY-129768 CMLD012072 Inhibitor / Unkown
HY-176843 eIF4A-IN-2 Inhibitor / Unkown
HY-RS04271 EIF4A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04275 EIF4E2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04278 EIF4EBP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04282 EIF4G2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17097 Eif4b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20664 Eif4ebp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21121 Eif4a2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27175 Eif4ebp2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27640 Eif4a2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eif4a2 NCBI NCBI:1974