Epha5 - Eph receptor A5 Gene

Also Known as bsk; Cek7; Ehk1; Els1; Hek7; Rek7

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13839

Summary

Enables GPI-linked Ephrin Receptor activity. Involved in several processes, including Ephrin Receptor signaling pathway; nervous system development; and regulation of Insulin secretion involved in cellular response to glucose stimulus. Acts upstream of or within cellular response to follicle-stimulating hormone stimulus and cellular response to forskolin. Located in adherens junction and cell periphery. Is expressed in several structures, including future midbrain; genitourinary system; nervous system; sensory organ; and upper jaw. Orthologous to human EphA5 (EPH receptor A5). [provided by Alliance of Genome Resources, Apr 2022]

Epha5 Products (14)

mRNA Protein Name
NM_001402749.1 NP_001389678.1 ephrin type-A receptor 5 isoform 1 precursor
NM_001402750.1 NP_001389679.1 ephrin type-A receptor 5 isoform 2 precursor
NM_001402751.1 NP_001389680.1 ephrin type-A receptor 5 isoform 3 precursor
NM_001402752.1 NP_001389681.1 ephrin type-A receptor 5 isoform 4
NM_001402753.1 NP_001389682.1 ephrin type-A receptor 5 isoform 5
NM_001402754.1 NP_001389683.1 ephrin type-A receptor 5 isoform 6
NM_001402755.1 NP_001389684.1 ephrin type-A receptor 5 isoform 7
NM_001402756.1 NP_001389685.1 ephrin type-A receptor 5 isoform 9
NM_001402757.1 NP_001389686.1 ephrin type-A receptor 5 isoform 10
NM_001402758.1 NP_001389687.1 ephrin type-A receptor 5 isoform 11 precursor
NM_001402759.1 NP_001389688.1 ephrin type-A receptor 5 isoform 12
NM_001402760.1 NP_001389689.1 ephrin type-A receptor 5 isoform 13
NM_001402761.1 NP_001389690.1 ephrin type-A receptor 5 isoform 14 precursor
NM_007937.3 NP_031963.2 ephrin type-A receptor 5 isoform 8 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GPI-linked ephrin receptor activity IDA
IDA: Inferred from direct assay
17448994 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9883724 MGI
Biological Process GO Annotation Evidence References Source
involved in axon guidance IDA
IDA: Inferred from direct assay
12124402 MGI
acts upstream of or within cellular response to follicle-stimulating hormone stimulus IDA
IDA: Inferred from direct assay
23242526 MGI
acts upstream of or within cellular response to forskolin IDA
IDA: Inferred from direct assay
23242526 MGI
involved in ephrin receptor signaling pathway IDA
IDA: Inferred from direct assay
17448994 MGI
involved in hippocampus development IDA
IDA: Inferred from direct assay
12124402 MGI
involved in regulation of GTPase activity IDA
IDA: Inferred from direct assay
17448994 MGI
involved in regulation of actin cytoskeleton organization IDA
IDA: Inferred from direct assay
17448994 MGI
involved in regulation of insulin secretion involved in cellular response to glucose stimulus IDA
IDA: Inferred from direct assay
17448994 MGI
Cellular Component GO Annotation Evidence References Source
located in adherens junction IDA
IDA: Inferred from direct assay
23242526 MGI
located in cell periphery IDA
IDA: Inferred from direct assay
23242526 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ephrin type-A receptor 5

  • EPH homology kinase 1

  • brain-specific kinase

  • eck-like sequence 1

Recombinant Epha5 Proteins

Cat. No. Product Name Accession Purity
HY-P77932 EPHA5 Protein, Mouse (HEK293, His) Q60629 (P27-P412) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04429 EPHA5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-146375 UniPR505 Antagonist 99.68% Unkown
HY-10654 EphB4-IN-2 Inhibitor / Unkown
HY-RS18661 Epha5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25147 Epha5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992403 MBRC-101 Antibody Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Epha5 NCBI NCBI:2044