Il25 - interleukin 25 Gene

Also Known as IL-25; Il17e; IL-17e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 140806

Summary

Enables cytokine activity. Acts upstream of or within several processes, including eosinophil differentiation; response to fungus; and response to nematode. Predicted to be located in extracellular space. Orthologous to human IL25 (interleukin 25). [provided by Alliance of Genome Resources, Apr 2022]

Il25 Products (1)

mRNA Protein Name
NM_080729.3 NP_542767.1 interleukin-25 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables cytokine activity IDA
IDA: Inferred from direct assay
12077275 MGI
Biological Process GO Annotation Evidence References Source
involved in T-helper 2 cell cytokine production IDA
IDA: Inferred from direct assay
19155511 MGI
acts upstream of or within eosinophil differentiation IDA
IDA: Inferred from direct assay
12077275 MGI
acts upstream of or within inflammatory response IDA
IDA: Inferred from direct assay
12077275 MGI
acts upstream of or within inflammatory response IMP
IMP: Inferred from mutant phenotype
11714825 MGI
acts upstream of or within interleukin-13 production IDA
IDA: Inferred from direct assay
18768888 MGI
acts upstream of or within interleukin-5 production IDA
IDA: Inferred from direct assay
18768888 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
21460847 MGI
acts upstream of or within response to fungus IDA
IDA: Inferred from direct assay
12077275 MGI
acts upstream of or within response to nematode IDA
IDA: Inferred from direct assay
11714825 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-25

  • interleukin 17E

Recombinant Il25 Proteins

Cat. No. Product Name Accession Purity
HY-P73198 IL-25/IL-17E Protein, Mouse (HEK293, His, solution) Q8VHH8 (V17-A169) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P700201AF Animal-Free IL-25/IL-17E Protein, Mouse (His) Q8VHH8 (V17-A169) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P991266 SM-17 Inhibitor 96.98% Phase 2

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06744 IL25 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08889 MYDGF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17706 Mydgf Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22207 Il25 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28729 Il25 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990216 Anti-Mouse IL-25 Antibody (2C3) Inhibitor 95.00% Unkown
HY-P991103 Anti-IL-25 Antibody Inhibitor 99.60% Unkown
HY-P991278 ABM-125 Inhibitor 96.92% Unkown
HY-P992244 Anti-IL25/IL17E Antibody (ABM109.2) Inhibitor / Unkown
HY-P992486 XKH001 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il25 NCBI NCBI:64806