NRG4 - neuregulin 4 Gene

Homo sapiens

Also known as HRG4

Gene ID: 145957 | Gene type: protein coding

About NRG4

Cytogenetic location: 15q24.2 Genomic coordinates (GRCh38): 15:75,935,393-76,060,240 (from NCBI)

This gene has 16 transcripts (splice variants), 103 orthologues and 3 paralogues. Ubiquitous expression in prostate (RPKM 2.0), skin (RPKM 1.9) and 25 other tissues.

Summary

The Neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR; MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]).[supplied by OMIM, Mar 2008]

NRG4 Products(1)

mRNA	Protein	Name
NM_138573.4	NP_612640.1	pro-neuregulin-4, membrane-bound isoform

Protein Preferred Names

Protein Names

pro-neuregulin-4, membrane-bound isoform

heregulin 4

Recombinant NRG4 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76524	Neuregulin-4/NRG4 Protein, Human	Q8WWG1 (GP&P2-F62)	≥95%

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09569	NRG4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	NRG4	VGNC	VGNC:84411
Rattus norvegicus	NRG4	RGD	RGD:1589860
Felis catus	NRG4	VGNC	VGNC:80904
Mus musculus	NRG4	MGD	MGI:1933833
Others	NRG4	NCBI