2. Gene
  3. Slc6a9 - solute carrier family 6 (neurotransmitter transporter, glycine), member 9 Gene

Slc6a9 - solute carrier family 6 (neurotransmitter transporter, glycine), member 9 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Glyt1; Glyt-1

Gene ID: 14664 | Gene type: protein coding

About Slc6a9

Chromosome 4: 117,691,703-117,732,395 forward strand.GRCm39:CM000997.3

This gene has 12 transcripts (splice variants), 206 orthologues, 20 paralogues and is associated with 25 phenotypes. Ubiquitous expression in liver E14.5 (RPKM 33.4), cerebellum adult (RPKM 3.9) and 27 other tissues.

Summary

Enables glycine transmembrane transporter activity. Involved in glycine import across plasma membrane; neurotransmitter uptake; and positive regulation of cellular biosynthetic process. Acts upstream of or within glycine secretion, neurotransmission. Located in plasma membrane. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and liver and biliary system. Used to study glycine encephalopathy. Orthologous to human SLC6A9 (solute carrier family 6 member 9). [provided by Alliance of Genome Resources, Apr 2022]

Slc6a9 Products(4)

mRNA Protein Name
NM_001355175.2 NP_001342104.1 sodium- and chloride-dependent glycine transporter 1 isoform 2
NM_001369017.1 NP_001355946.1 sodium- and chloride-dependent glycine transporter 1 isoform 3 precursor
NM_001369016.1 NP_001355945.1 sodium- and chloride-dependent glycine transporter 1 isoform 1
NM_008135.4 NP_032161.2 sodium- and chloride-dependent glycine transporter 1 isoform 1

Slc6a9 Protein Structure

SLC6sbd_GlyT1

SLC6sbd_GlyT1: cd11498 (10 - 593)

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  • 633 a.a.
Protein Preferred Names Protein Names

sodium- and chloride-dependent glycine transporter 1

glycine transporter 1

solute carrier family 6 member 9

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13320 SLC6A9 Human Pre-designed siRNA Set A / Unkown
HY-RS13321 Slc6a9 Mouse Pre-designed siRNA Set A / Unkown
HY-RS13322 Slc6a9 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc6a9 NCBI NCBI:6536