Ltc4s - leukotriene C4 synthase Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17001

Summary

The protein encoded by this gene is an enzyme that catalyzes the synthesis of leukotriene C4 by combining leukotriene A4 with reduced glutathione. The encoded protein is found in the outer nuclear membrane and in the peripheral endoplasmic reticulum. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as bronchial asthma in humans. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

Ltc4s Products (2)

mRNA Protein Name
NM_001313968.1 NP_001300897.1 leukotriene C4 synthase isoform 2
NM_008521.2 NP_032547.1 leukotriene C4 synthase isoform 1
Protein Preferred Names Protein Names

leukotriene C4 synthase

  • LTC4 synthase

  • glutathione S-transferase LTC4

  • leukotriene-C(4) synthase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-126329 AZD9898 Inhibitor 98.01% Phase 1

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-117143 TK05 Inhibitor 97.05% Unkown
HY-168498 GJG057 Inhibitor 98.82% Unkown
HY-RS07882 LTC4S Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21637 Ltc4s Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28155 Ltc4s Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ltc4s NCBI NCBI:4056