Cd180 - CD180 antigen Gene

Also Known as Ly78; Ly-78; RP105; F630107B15

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17079

Summary

Predicted to enable transmembrane signaling receptor activity. Acts upstream of or within B cell proliferation involved in immune response; cellular response to lipopolysaccharide; and positive regulation of lipopolysaccharide-mediated signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in extracellular matrix and extracellular space. Orthologous to human CD180 (CD180 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd180 Products (2)

mRNA Protein Name
NM_001360519.1 NP_001347448.1 CD180 antigen isoform 2
NM_008533.2 NP_032559.2 CD180 antigen isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
9686597 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within B cell proliferation involved in immune response IMP
IMP: Inferred from mutant phenotype
10880523 MGI
acts upstream of or within cellular response to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
10880523 MGI
acts upstream of lipopolysaccharide-mediated signaling pathway IGI
IGI: Inferred from genetic interaction
10880523 MGI
acts upstream of or within positive regulation of lipopolysaccharide-mediated signaling pathway IGI
IGI: Inferred from genetic interaction
10880523 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CD180 antigen

  • lymphocyte antigen 78

  • radioprotective 105 kDa protein

Cd180 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Cd180 Q62192 Ly86 Mus musculus O88188
CoIP
9686597
Intra
Cd180 Q62192 Ly86 Mus musculus O88188
Pull Down
21857663
Intra
Cd180 Q62192 Ly86 Mus musculus O88188
GMS
21857663
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Cd180 Proteins

Cat. No. Product Name Accession Purity
HY-P77182 RP105/CD180 Protein, Mouse (HEK293, Fc) Q62192 (M1-S626) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P77183 RP105/CD180 Protein, Mouse (HEK293, His) Q62192 (M1-S626) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02197 CD180 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19415 Cd180 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25907 Cd180 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991956 ABB071 Inhibitor / Unkown
HY-P992204 Anti-CD180 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd180 NCBI NCBI:4064