Sumo2 - small ubiquitin-like modifier 2 Gene

Also Known as Smt3A; Smt3b; SUMO-2; Smt3h2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 170930

Summary

Enables SUMO transferase activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II and protein sumoylation. Predicted to be located in PML body. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; eye; heart; and metanephros. Orthologous to human SUMO2 (small ubiquitin like modifier 2). [provided by Alliance of Genome Resources, Apr 2022]

Sumo2 Products (2)

mRNA Protein Name
NM_133354.2 NP_579932.1 small ubiquitin-related modifier 2
NM_133354.2 NP_579932.1 small ubiquitin-related modifier 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables SUMO transferase activity IDA
IDA: Inferred from direct assay
15767674 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
31088288 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
21931855 MGI
acts upstream of or within protein sumoylation IDA
IDA: Inferred from direct assay
15767674 MGI
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
37009224 MGI
is active in GABA-ergic synapse IEP
IEP: Inferred from expression pattern
37009224 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
31749687 MGI
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: Inferred from direct assay
37009224 MGI
is active in hippocampal mossy fiber to CA3 synapse IEP
IEP: Inferred from expression pattern
37009224 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
37009224 MGI
is active in postsynapse IEP
IEP: Inferred from expression pattern
37009224 MGI
is active in postsynaptic cytosol IDA
IDA: Inferred from direct assay
31749687 MGI
is active in presynapse IDA
IDA: Inferred from direct assay
37009224 MGI
is active in presynapse IEP
IEP: Inferred from expression pattern
37009224 MGI
is active in presynaptic cytosol IDA
IDA: Inferred from direct assay
31749687 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

small ubiquitin-related modifier 2

  • SMT3 homolog 2

  • SMT3 suppressor of mif two 3 homolog 2

  • SMT3 supressor of mif two 3 homolog 2

  • sentrin-2

  • ubiquitin-like protein SMT3A

  • ubiquitin-like protein SMT3B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-108702 ML-792 Inhibitor 99.76% Unkown
HY-RS18410 Sumo2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14026 SUMO2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24891 Sumo2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sumo2 NCBI NCBI:6613