Dnph1 - 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 Gene

Also Known as Rcl; C6orf108; RGD620382

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171047

Summary

Enables deoxyribonucleoside 5'-monophosphate N-glycosidase activity and protein homodimerization activity. Involved in allantoin metabolic process; dGMP catabolic process; and positive regulation of cell growth. Located in nucleus. Orthologous to human DNPH1 (2'-deoxynucleoside 5'-phosphate N-hydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Dnph1 Products (1)

mRNA Protein Name
NM_133525.2 NP_598209.1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables deoxyribonucleoside 5'-monophosphate N-glycosidase activity IDA
IDA: Inferred from direct assay
17234634 RGD
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
17234634 RGD
Biological Process GO Annotation Evidence References Source
involved in allantoin metabolic process IDA
IDA: Inferred from direct assay
17234634 RGD
involved in dGMP catabolic process IDA
IDA: Inferred from direct assay
17234634 RGD
involved in deoxyribonucleoside monophosphate catabolic process IDA
IDA: Inferred from direct assay
17234634 RGD
involved in positive regulation of cell growth IDA
IDA: Inferred from direct assay
17234634 RGD
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
9271375 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

2'-deoxynucleoside 5'-phosphate N-hydrolase 1

  • Nucleoside 2-deoxyribosyltransferase domain containing protein RGD620382

  • c-Myc-responsive protein Rcl

  • deoxyribonucleoside 5'-monophosphate N-glycosidase

  • putative c-Myc-responsive

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-179268 DNPH1-IN-1 Inhibitor / Unkown
HY-179303 DNPH1 ligand-1 / Unkown
HY-179582 PROTAC DNPH1 Degrader 1 Degrader / Unkown
HY-RS03915 DNPH1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19676 Dnph1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26169 Dnph1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dnph1 NCBI NCBI:10591