Dusp5 - dual specificity phosphatase 5 Gene

Also Known as Cpg21

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171109

Summary

Enables MAP kinase tyrosine/serine/threonine Phosphatase activity. Involved in negative regulation of transcription, DNA-templated; negative regulation of vasoconstriction; and positive regulation of cerebral blood circulation. Predicted to be active in cytoplasm and nucleus. Orthologous to human DUSP5 (dual specificity Phosphatase 5). [provided by Alliance of Genome Resources, Apr 2022]

Dusp5 Products (1)

mRNA Protein Name
NM_133578.2 NP_598262.2 dual specificity protein phosphatase 5

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables MAP kinase tyrosine/serine/threonine phosphatase activity IDA
IDA: Inferred from direct assay
9699150 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
9699150 RGD
involved in negative regulation of vasoconstriction IMP
IMP: Inferred from mutant phenotype
25397684 RGD
involved in positive regulation of cerebral blood circulation IMP
IMP: Inferred from mutant phenotype
25397684 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dual specificity protein phosphatase 5

  • MAP-kinase phosphatase (cpg21)

  • MAP-kinase phosphatase CPG21

  • candidate plasticity-related gene 21

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-202699 SHOC2-RAS PPI-IN-1 Inhibitor 99.50% Unkown
HY-RS04066 DUSP5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19431 Dusp5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25922 Dusp5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dusp5 NCBI NCBI:1847