Madcam1 - mucosal vascular addressin cell adhesion molecule 1 Gene

Also Known as MAdCAM-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17123

Summary

Predicted to enable Integrin binding activity involved in cell-matrix adhesion. Acts upstream of or within keratinocyte differentiation and leukocyte migration. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in eyelid; hair follicle; and hemolymphoid system. Orthologous to human MADCAM1 (mucosal vascular addressin cell adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Madcam1 Products (2)

mRNA Protein Name
NM_001358785.1 NP_001345714.1 mucosal addressin cell adhesion molecule 1 isoform 2 precursor
NM_013591.3 NP_038619.2 mucosal addressin cell adhesion molecule 1 isoform 1 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within keratinocyte differentiation IMP
IMP: Inferred from mutant phenotype
12230506 MGI
acts upstream of or within leukocyte migration IMP
IMP: Inferred from mutant phenotype
15484189 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mucosal addressin cell adhesion molecule 1

  • cell adhesion molecule 1

Recombinant Madcam1 Proteins

Cat. No. Product Name Accession Purity
HY-P77748 MAdCAM1 Protein, Mouse (HEK293, His) Q61826-1 (Q22-S364) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99411 Ontamalimab 99.86% Phase 3

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-159179 α4 integrin receptor antagonist 3 Inhibitor / Unkown
HY-171216 GW559090 Antagonist / Unkown
HY-177961 α4β7 Integrin-IN-1 Inhibitor / Unkown
HY-RS07952 MADCAM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19091 Madcam1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25581 Madcam1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990203 Anti-Mouse LPAM-1/Integrin α4β7 Antibody (DATK32) Inhibitor 99.08% Unkown
HY-P991807 Anti-Mouse MAdCAM-1 Antibody (MECA-89) Inhibitor / Unkown
HY-P990197 Anti-Mouse MAdCAM-1 Antibody (MECA-367) Inhibitor 96.72% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Madcam1 NCBI NCBI:8174
Macaca fascicularis Madcam1 NCBI NCBI:102125701