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Ontamalimab

(Synonyms: SHP647)
1 Cited Publications
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Based on 1 publication(s) in Google Scholar

Ontamalimab (SHP647) is a fully-human IgG2 monoclonal antibody targeting mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Ontamalimab can be used for the research of Crohn's disease.

For research use only. We do not sell to patients.

  • Purity: 99.86%
  • CAS No.: 2098790-40-8
  • Molecular Weight:146.84 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Ontamalimab
  • Experimental Validation Results for Ontamalimab
  • Experimental Validation Results for Ontamalimab
  • Ontamalimab Chemical Structure
    Ontamalimab Chemical Structure
CAS No.: 2098790-40-8
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Ontamalimab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG2 kappa

  • 1/16

    Immobilized MAdCAM1 Protein, Human (HEK293, His, HY-P70852) can bind Ontamalimab. The EC50 for this effect is 25.81 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 HUVEC cells with Ontamalimab (HY-P99411, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa (HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Ontamalimab Chemical Structure
    1/16
  • Ontamalimab
  • Immobilized MAdCAM1 Protein, Human (HEK293, His, HY-P70852) can bind Ontamalimab. The EC50 for this effect is 25.81 ng/mL.
  • Flow cytometric analysis of 1X106 HUVEC cells with Ontamalimab (HY-P99411, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa (HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).