SGK3 - serum/glucocorticoid regulated kinase family, member 3 Gene
Also Known as Cisk; Sgkl
Species: Rattus norvegicus
About SGK3
This gene has 1 transcript (splice variant), 212 orthologues, 13 paralogues and is associated with 2 phenotypes. Biased expression in Spleen (RPKM 13.9), Thymus (RPKM 9.3) and 9 other tissues.
Summary
Predicted to enable Potassium Channel regulator activity and protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Predicted to act upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand. Predicted to be located in cytoplasmic vesicle and nucleoplasm. Orthologous to several human genes including C8orf44-SGK3 (C8orf44-SGK3 readthrough). [provided by Alliance of Genome Resources, Apr 2022]
SGK3 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001376043.1 | NP_001362972.1 | serine/threonine-protein kinase Sgk3 |
SGK3 Protein Structure
PX_CISK: cd06870 (11 - 119)
STKc_SGK3: cd05604 (164 - 489)
- 0
- 100
- 200
- 300
- 400
- 496 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
serine/threonine-protein kinase Sgk3 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-125878 | PROTAC SGK3 degrader-1 | Inhibitor | 99.89% | Unkown |
| HY-167832 | PT109 | Inhibitor | 99.20% | Unkown |
| HY-170933 | SGK1-IN-6 | Inhibitor | / | Unkown |
| HY-151009 | 308-R | Inhibitor | / | Unkown |
| HY-W260045 | 1-Chloro-6-methoxyhexane | Ligand | / | Unkown |
| HY-176823 | PROTAC SGK3 degrader-2 | Degrader | / | Unkown |
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