Nudt1 - nudix hydrolase 1 Gene

Also Known as Mth1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17766

Summary

Enables 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity and snoRNA binding activity. Predicted to be involved in DNA protection and purine nucleoside catabolic process. Predicted to be located in several cellular components, including acrosomal vesicle; mitochondrial matrix; and nuclear membrane. Predicted to be active in cytoplasm. Orthologous to human NUDT1 (nudix hydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Nudt1 Products (4)

mRNA Protein Name
NM_001356583.1 NP_001343512.1 oxidized purine nucleoside triphosphate hydrolase
NM_001356584.1 NP_001343513.1 oxidized purine nucleoside triphosphate hydrolase
NM_001356585.1 NP_001343514.1 oxidized purine nucleoside triphosphate hydrolase
NM_008637.2 NP_032663.1 oxidized purine nucleoside triphosphate hydrolase

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
NOT enables 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity IDA
IDA: Inferred from direct assay
21070968 MGI
enables 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity IDA
IDA: Inferred from direct assay
7592783 MGI
enables snoRNA binding IDA
IDA: Inferred from direct assay
21070968 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

oxidized purine nucleoside triphosphate hydrolase

7,8-dihydro-8-oxoguanine triphosphatase

  • 2-hydroxy-dATP diphosphatase

  • 8-oxo-7,8-dihydro-2'-dGTPase

  • 8-oxo-dGTPase

  • methylated purine nucleoside triphosphate hydrolase

  • mutT human homolog (8-oxo-dGTPase)

  • nucleoside diphosphate-linked moiety X motif 1

  • nudix (nucleoside diphosphate linked moiety

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112081 BAY-707 Inhibitor 99.64% Unkown
HY-158062 LC-1-40 99.65% Unkown
HY-187054 NUDT1 ligand-1 Ligand / Unkown
HY-RS09661 NUDT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18535 Nudt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25017 Nudt1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nudt1 NCBI NCBI:4521