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Cat. No.: HY-189207

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NUDT1-IN-1

NUDT1-IN-1 is an inhibitor of NUDT1 (MTH1) with a pIC₅₀ value of 9.785. NUDT1-IN-1 can be applied in cancer research.

For research use only. We do not sell to patients.

Formula: C₂₈H₃₄O₆
Molecular Weight:466.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

NUDT1-IN-1 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

NUDT1-IN-1 is an inhibitor of NUDT1 (MTH1) with a pIC₅₀ value of 9.785. NUDT1-IN-1 can be applied in cancer research^[1].

All DNA/RNA Synthesis Isoforms :

In Vitro

NUDT1-IN-1 (Structure 1) exhibits the strongest inhibitory activity against MTH1, with the highest experimentally determined pIC₅₀ value of 9.785^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 466.57
Formula C₂₈H₃₄O₆
SMILES

CC1=C[C@@]2([H])[C@@]([C@@H]1O)(O)CC(CO)=C[C@@]3([H])[C@@]2(O4)[C@@H](C)C[C@]5(C(C)=C)[C@@]3([H])O[C@@]4(CC6=CC=CC=C6)O5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Tasnim J, et al. In silico identification of a potential NUDT1 inhibitor for cancer treatment[J]. Scientific Reports, 2026.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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