Npas2 - neuronal PAS domain protein 2 Gene

Also Known as MOP4; bHLHe9

Species: Mus musculus

Gene Type: protein coding

Gene ID: 18143

Summary

The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. The encoded protein may play a regulatory role in the acquisition of specific types of memory. It also may function as a part of a molecular clock operative in the mammalian forebrain. [provided by RefSeq, Dec 2014]

Npas2 Products (1)

mRNA	Protein	Name
NM_008719.2	NP_032745.2	neuronal PAS domain-containing protein 2

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	References	Source
enables DNA binding	IDA IDA: Inferred from direct assay	23831463	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	14645221	MGI

Biological Process GO Annotation	Evidence	References	Source
involved in circadian regulation of gene expression	IMP IMP: Inferred from mutant phenotype	18316400	MGI
involved in circadian rhythm	IEP IEP: Inferred from expression pattern	14645221	MGI
acts upstream of or within circadian sleep/wake cycle	IMP IMP: Inferred from mutant phenotype	12843397	MGI
acts upstream of or within locomotor rhythm	IMP IMP: Inferred from mutant phenotype	12843397	MGI
involved in positive regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	18316400	MGI
involved in positive regulation of DNA-templated transcription	IMP IMP: Inferred from mutant phenotype	25212631	MGI
involved in positive regulation of behavioral fear response	IMP IMP: Inferred from mutant phenotype	29163035	MGI
involved in regulation of circadian rhythm	IMP IMP: Inferred from mutant phenotype	24048828	MGI
involved in response to redox state	IDA IDA: Inferred from direct assay	23831463	MGI
involved in response to xenobiotic stimulus	IMP IMP: Inferred from mutant phenotype	29163035	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
neuronal PAS domain-containing protein 2	neuronal PAS2

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09469	NPAS2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21002	Npas2 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27519	Npas2 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Npas2	NCBI	NCBI:4862