Pcolce - procollagen C-endopeptidase enhancer protein Gene

Also Known as P14; Astt2; Astt-2; PCPE-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18542

About Pcolce

Chromosome 5: 137,603,365-137,612,046 reverse strand.GRCm39:CM000998.3

This gene has 12 transcripts (splice variants), 246 orthologues, 35 paralogues and is associated with 9 phenotypes. Biased expression in adrenal adult (RPKM 519.4), ovary adult (RPKM 131.5) and 9 other tissues.

Summary

Predicted to enable Collagen binding activity; heparin binding activity; and peptidase activator activity. Acts upstream of or within cellular response to Leukemia Inhibitory Factor and proteolysis. Located in extracellular space. Is expressed in several structures, including adrenal gland; branchial arch; embryo endoderm; lower jaw; and umbilical blood vessel. Orthologous to human PCOLCE (procollagen C-endopeptidase enhancer). [provided by Alliance of Genome Resources, Apr 2022]

Pcolce Products (1)

mRNA Protein Name
NM_008788.2 NP_032814.2 procollagen C-endopeptidase enhancer 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
26220971 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
acts upstream of or within proteolysis IDA
IDA: Inferred from direct assay
7523404 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Pcolce Protein Structure

CUB

CUB: cd00041 (35 - 145)

CUB

CUB: cd00041 (157 - 270)

NTR_PCOLCE

NTR_PCOLCE: cd03576 (333 - 459)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 468 a.a.
Protein Preferred Names Protein Names

procollagen C-endopeptidase enhancer 1

  • astroglial cell transcript 2

  • procollagen C-proteinase enhancer 1

  • procollagen C-proteinase enhancer protein

  • procollagen COOH-terminal proteinase enhancer 1

  • type 1 procollagen C-proteinase enhancer protein

  • type I procollagen COOH-terminal proteinase enhancer

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10163 PCOLCE Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10164 Pcolce Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10165 Pcolce Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10166 PCOLCE2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21248 Pcolce2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27765 Pcolce2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pcolce NCBI NCBI:5118