Pnmt - phenylethanolamine-N-methyltransferase Gene

Also Known as Pent

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18948

Summary

Predicted to enable phenylethanolamine N-methyltransferase activity. Predicted to be involved in epinephrine biosynthetic process and norepinephrine metabolic process. Predicted to act upstream of or within Catecholamine biosynthetic process and methylation. Predicted to be located in several cellular components, including axon; dendrite; and perikaryon. Predicted to be active in cytosol. Is expressed in several structures, including adrenal gland; brain; gonad; and metanephros. Human ortholog(s) of this gene implicated in Alzheimer's disease; hypertension; and multiple sclerosis. Orthologous to human PNMT (phenylethanolamine N-methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Pnmt Products (1)

mRNA Protein Name
NM_008890.3 NP_032916.1 phenylethanolamine N-methyltransferase

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables phenylethanolamine N-methyltransferase activity IDA
IDA: Inferred from direct assay
17698731 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phenylethanolamine N-methyltransferase

  • PNMTase

  • noradrenaline N-methyltransferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-142110 LY 78335 Inhibitor 99.19% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pnmt NCBI NCBI:5409