2. Gene
  3. Pde9a - phosphodiesterase 9A Gene

Pde9a - phosphodiesterase 9A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 191569 | Gene type: protein coding

About Pde9a

Primary_assembly 20: 9,469,848-9,562,948 forward strand.mRatBN7.2:CM026993.1

This gene has 5 transcripts (splice variants), 192 orthologues, 20 paralogues and is associated with 6 phenotypes. Biased expression in Lung (RPKM 75.8), Kidney (RPKM 67.7) and 7 other tissues.

Summary

Enables 3',5'-cyclic-GMP phosphodiesterase activity. Involved in cGMP-mediated signaling. Located in perikaryon. Orthologous to human PDE9A (phosphodiesterase 9A). [provided by Alliance of Genome Resources, Apr 2022]

Pde9a Products(1)

mRNA Protein Name
NM_138543.1 NP_612552.1 high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Pde9a Protein Structure

PDEase_I

PDEase_I: pfam00233 (249 - 477)

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  • 534 a.a.
Protein Preferred Names Protein Names

high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-15441 Edelinontrine Inhibitor 98.74% Phase 2
HY-112831 Osoresnontrine Inhibitor 99.88% Phase 2
Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-104028 BAY 73-6691 Inhibitor 99.84% Unkown
HY-12788 PF-04449613 Inhibitor 99.83% Unkown
HY-126137 PDE9-IN-1 Inhibitor 99.70% Unkown
HY-12788A (S)-PF-04449613 Inhibitor 99.85% Unkown
HY-152106 BAY-7081 Inhibitor / Unkown
HY-104028B (S)-BAY 73-6691 99.51% Unkown
HY-RS10246 PDE9A Human Pre-designed siRNA Set A / Unkown
HY-RS10247 Pde9a Mouse Pre-designed siRNA Set A / Unkown
HY-RS10248 Pde9a Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pde9a NCBI NCBI:5152