Ranbp2 - RAN binding protein 2 Gene

Also Known as NUP358; A430087B05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19386

Summary

Enables SUMO transferase activity. Acts upstream of or within positive regulation of Glucokinase activity and regulation of gluconeogenesis. Located in mitochondrion. Is expressed in several structures, including alimentary system; early conceptus; hemolymphoid system; nervous system; and reproductive system. Human ortholog(s) of this gene implicated in brain disease and inflammatory myofibroblastic tumor. Orthologous to several human genes including RANBP2 (RAN binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Ranbp2 Products (1)

mRNA Protein Name
NM_011240.3 NP_035370.2 E3 SUMO-protein ligase RanBP2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables SUMO transferase activity EXP
EXP: Inferred from Experiment
18394993 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16332688 MGI
Biological Process GO Annotation Evidence References Source
involved in nuclear export EXP
EXP: Inferred from Experiment
27160050 MGI
acts upstream of or within positive regulation of glucokinase activity IDA
IDA: Inferred from direct assay
17069463 MGI
acts upstream of or within regulation of gluconeogenesis IMP
IMP: Inferred from mutant phenotype
17069463 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 SUMO-protein ligase RanBP2

  • E3 SUMO-protein transferase RanBP2

  • ran-binding protein 2

Ranbp2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Ranbp2 Q9ERU9 Prkn Mus musculus Q9WVS6
Anti Bait CoIP
16332688
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11645 RANBP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ranbp2 NCBI NCBI:5903