PLBD2 - phospholipase B domain containing 2 Gene

Homo sapiens

Also known as P76

Gene ID: 196463 | Gene type: protein coding

About PLBD2

Cytogenetic location: 12q24.13 Genomic coordinates (GRCh38): 12:113,358,587-113,391,629 (from NCBI)

This gene has 4 transcripts (splice variants), 193 orthologues and 1 paralogue. Ubiquitous expression in adrenal (RPKM 36.9), ovary (RPKM 20.4) and 25 other tissues.

Summary

Predicted to enable Phospholipase activity. Predicted to be involved in phospholipid catabolic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

PLBD2 Products(2)

mRNA	Protein	Name
NM_001159727.2	NP_001153199.1	putative phospholipase B-like 2 isoform 2 precursor
NM_173542.4	NP_775813.2	putative phospholipase B-like 2 isoform 1 precursor

PLBD2 Protein Structure

Phospholip_B

0
100
200
300
400
500
589 a.a.

Protein Preferred Names

Protein Names

putative phospholipase B-like 2

76 kDa protein

Recombinant PLBD2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77148	PLBD2 Protein, Human (HEK293, His)	Q8NHP8-1 (I42-D589)	≥95%

Related Diseases

Diseases

Alias

Gallbladder Papillomatosis

Sea-Blue Histiocyte Disease

Sea-Blue Histiocytosis	Sea-Blue Histiocyte Syndrome
Histiocytosis, Sea-Blue	Inherited Lipemic Splenomegaly
SBHD

Gm1-Gangliosidosis, Type Iii

Gm1 Gangliosidosis Type 3	GM1G3
Gangliosidosis, Generalized Gm1, Type 3	Adult-Onset Gm1 Gangliosidosis
Gangliosidosis Gm1 Type 3	Gangliosidosis Generalized Gm1 Chronic Type
Gangliosidosis, Generalized Gm1, Adult Type	Gangliosidosis, Generalized Gm1, Chronic Type
Gangliosidosis, Generalized Gm1, Type Iii	Adult Gm1 Gangliosidosis
Beta-Galactosidase Deficiency Type 3	Gm1-Gangliosidosis 3
Gangliosidosis Generalized Gm1 Type 3	Gm1-Gangliosidosis Generalized Adult Type
Gangliosidosis, Gm1 Type Iii

Gaucher Disease, Type Iiic

Gaucher Disease-Ophthalmoplegia-Cardiovascular Calcification Syndrome	Gaucher-Like Disease
GD3C	Gaucher'S Disease Type Iiic
Cardiovascular Gaucher Disease	Gaucher Disease Type 3c
Gaucher Disease 3c	Pseudo-Gaucher Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10651	PLBD2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	PLBD2	MGD	MGI:1919022
Canis familiaris	PLBD2	VGNC	VGNC:44643
Felis catus	PLBD2	VGNC	VGNC:64207
Macaca mulatta	PLBD2	VGNC	VGNC:76122
Rattus norvegicus	PLBD2	RGD	RGD:708461
Bos taurus	PLBD2	VGNC	VGNC:32979
Others	PLBD2	NCBI

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