S100a8 - S100 calcium binding protein A8 (calgranulin A) Gene

Also Known as p8; B8Ag; CFAg; Caga; MRP8; CP-10; 60B8Ag

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20201

Summary

Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Acts upstream of or within astrocyte development and positive regulation of peptide secretion. Predicted to be located in cytosol and intermediate filament Cytoskeleton. Predicted to be active in extracellular space. Is expressed in several structures, including bone marrow; extraembryonic component; female reproductive system; and liver. Human ortholog(s) of this gene implicated in myocarditis. Orthologous to human S100A8 (S100 calcium binding protein A8). [provided by Alliance of Genome Resources, Apr 2022]

S100a8 Products (1)

mRNA Protein Name
NM_013650.2 NP_038678.1 protein S100-A8

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within astrocyte development IGI
IGI: Inferred from genetic interaction
22577135 MGI
acts upstream of peptide secretion IDA
IDA: Inferred from direct assay
18820689 MGI
acts upstream of peptide secretion IMP
IMP: Inferred from mutant phenotype
18820689 MGI
acts upstream of or within positive regulation of peptide secretion IDA
IDA: Inferred from direct assay
18820689 MGI
acts upstream of or within positive regulation of peptide secretion IMP
IMP: Inferred from mutant phenotype
18820689 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein S100-A8

  • MRP-8

  • S100 calcium-binding protein A8

  • calgranulin-A

  • chemotactic S100 protein

  • chemotactic cytokine CP-10

  • leukocyte L1 complex light chain

  • migration inhibitory factor-related protein 8

  • pro-inflammatory S100 cytokine

Recombinant S100a8 Proteins

Cat. No. Product Name Accession Purity
HY-P71779 S100A8 Protein, Mouse (P.pastoris, His) P27005 (P2-E89) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P73671 S100A8 Protein, Mouse (sf9, His) P27005 (M1-E89) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-100442 Paquinimod Inhibitor 99.90% Phase 2

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-141537 ABR-238901 Inhibitor 98.92% Unkown
HY-100442S1 Paquinimod-d5-1 Inhibitor 98.19% Unkown
HY-RS16593 S100a8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12385 S100A8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-100442S Paquinimod-d5 Inhibitor / Unkown
HY-RS23027 S100a8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens S100a8 NCBI NCBI:6279