Ccl20 - chemokine (C-C motif) ligand 20 Gene

Also Known as CKb4; LARC; ST38; MIP3A; MIP-3A; Scya20; MIP-3[a]; exodus-1

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 20297

Summary

Enables CCR6 Chemokine Receptor binding activity and cytokine activity. Involved in chemotaxis and thymocyte migration. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human CCL20 (C-C motif chemokine ligand 20). [provided by Alliance of Genome Resources, Apr 2022]

Ccl20 Products (2)

mRNA Protein Name
NM_001159738.1 NP_001153210.1 C-C motif chemokine 20 isoform 2 precursor
NM_016960.2 NP_058656.1 C-C motif chemokine 20 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables CCR6 chemokine receptor binding IDA
IDA: Inferred from direct assay
20068036 MGI
enables cytokine activity IDA
IDA: Inferred from direct assay
9862452 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9862452 MGI
Biological Process GO Annotation Evidence 参考文献 由来
involved in T cell migration IDA
IDA: Inferred from direct assay
19050256 MGI
involved in chemotaxis IDA
IDA: Inferred from direct assay
20068036 MGI
NOT involved in regulation of T cell cytokine production IDA
IDA: Inferred from direct assay
19050256 MGI
NOT involved in regulation of T-helper 17 cell differentiation IDA
IDA: Inferred from direct assay
19050256 MGI
involved in thymocyte migration IDA
IDA: Inferred from direct assay
24638065 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-C motif chemokine 20

  • CC chemokine LARC

  • CC chemokine ST38

  • MIP-3-alpha

  • beta-chemokine exodus-1

  • liver and activation-regulated chemokine

  • macrophage inflammatory protein 3 alpha

  • small inducible cytokine subfamily A20

  • small-inducible cytokine A20

Recombinant Ccl20 Proteins

製品番号 製品名 アクセッション番号 純度
HY-P7263 MIP-3 alpha/CCL20 Protein, Mouse O89093 (A28-M97) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73813 MIP-3 alpha/CCL20 Protein, Mouse (sf9, His) O89093 (A28-M97) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

阻害性抗体 (1)
製品番号 製品名 製品効果
純度 Phase
HY-P990592 GSK-3050002 97.30% Phase 1

Pre-clinical Phase

Bioactive Molecules (10)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-151435 CCR6 antagonist 1 Antagonist 99.30% Unkown
HY-19548A BEC hydrochloride Inhibitor 98.0% Unkown
HY-162495 IDOR-1117-2520 99.94% Unkown
HY-162495A (S)-IDOR-1117-2520 99.47% Unkown
HY-172161 CCR6 antagonist 2 Antagonist / Unkown
HY-178053 AHR agonist 10 / Unkown
HY-RS02090 CCL20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174762 Human CCL20 mRNA / Unkown
HY-RS16609 Ccl20 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23043 Ccl20 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Ccl20 NCBI NCBI:6364