CCR6 antagonist 2
CCR6 antagonist 2 (Compound 20c) is the antagonist for CCR6 with a Ki of 1.1 nM. CCR6 antagonist 2 inhibits CCL20-induced calcium ion influx (IC50 = 4.9 nM), inhibits the chemotactic migration of CCR6+ T cells (IC50 = 190 nM).
For research use only. We do not sell to patients.
- Formula: C19H24N4O4
- Molecular Weight:372.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 372.42
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Formula C19H24N4O4
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SMILES
O=C(N(C)C)C1=NC=CC(NC2=C(N[C@@H]3[C@H](C)CCCC3)C(C2=O)=O)=C1O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)