Ccl7 - chemokine (C-C motif) ligand 7 Gene

Also Known as fic; marc; mcp3; MCP-3; Scya7

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20306

Summary

Enables CCR2 Chemokine Receptor binding activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; leukocyte chemotaxis; and positive regulation of natural killer cell chemotaxis. Predicted to act upstream of or within chemotaxis. Located in extracellular space. Is expressed in several structures, including central nervous system; leg; lung; retina; and vertebral axis musculature. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human CCL7 (C-C motif chemokine ligand 7). [provided by Alliance of Genome Resources, Apr 2022]

Ccl7 Products (1)

mRNA Protein Name
NM_013654.3 NP_038682.1 C-C motif chemokine 7 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables CCR2 chemokine receptor binding IPI
IPI: Inferred from physical interaction
8662823 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
22960654 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-C motif chemokine 7

  • RANTES/sis homolog

  • intercrine/chemokine MARC

  • monocyte chemoattractant protein 3

  • monocyte chemotactic protein 3

  • small-inducible cytokine A7

Recombinant Ccl7 Proteins

Cat. No. Product Name Accession Purity
HY-P7243 MCP-3/CCL7 Protein, Mouse Q03366 (Q24-P97) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-B0498 Bindarit Inhibitor 99.59% Phase 3
HY-165528 Histamine glutarimide Inhibitor / Phase 3

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02106 CCL7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W505771 Seselin Inhibitor 99.55% Unkown
HY-174750 Human CCL7 mRNA / Unkown
HY-RS16708 Ccl7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23143 Ccl7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccl7 NCBI NCBI:6354