Lzts1 - leucine zipper, putative tumor suppressor 1 Gene

Also Known as F37; FEZ1; PSD-Zip70

Species: Mus musculus

Gene Type: protein coding
Gene ID: 211134

Summary

Predicted to enable microtubule binding activity. Predicted to be involved in negative regulation of macroautophagy; regulation of dendrite morphogenesis; and regulation of synaptic plasticity. Predicted to be located in several cellular components, including apical plasma membrane; dendritic shaft; and postsynaptic density. Predicted to be active in dendritic spine. Is expressed in several structures, including brain and metanephros. Human ortholog(s) of this gene implicated in esophageal Cancer and squamous cell carcinoma. Orthologous to human LZTS1 (leucine zipper tumor suppressor 1). [provided by Alliance of Genome Resources, Apr 2022]

Lzts1 Products (2)

mRNA Protein Name
NM_001370971.1 NP_001357900.1 leucine zipper putative tumor suppressor 1
NM_199364.3 NP_955396.2 leucine zipper putative tumor suppressor 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynapse assembly IDA
IDA: Inferred from direct assay
26490870 MGI
involved in regulation of postsynapse assembly IMP
IMP: Inferred from mutant phenotype
26490870 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
26490870 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
26490870 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine zipper putative tumor suppressor 1

  • F37 esophageal cancer-related leucine zipper motif 1

  • F37/Esophageal cancer-related gene-coding leucine-zipper motif

  • leucine-zipper protein FEZ1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07934 LZTS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22620 Lzts1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29135 Lzts1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lzts1 NCBI NCBI:11178