Taok1 - TAO kinase 1 Gene

Also Known as Psk2; Markk; Map3k16; 2810468K05Rik; D130018F14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 216965

Summary

Predicted to enable several functions, including cytoskeletal protein binding activity; protein C-terminus binding activity; and protein serine/threonine kinase activator activity. Predicted to be involved in several processes, including intracellular signal transduction; positive regulation of JNK cascade; and regulation of Cytoskeleton organization. Predicted to act upstream of or within DNA repair and apoptotic process. Predicted to be located in microtubule Cytoskeleton and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including adrenal gland; alimentary system; lung; nervous system; and retina. Orthologous to human TAOK1 (TAO kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Taok1 Products (3)

mRNA Protein Name
NM_001364133.1 NP_001351062.1 serine/threonine-protein kinase TAO1
NM_001364134.1 NP_001351063.1 serine/threonine-protein kinase TAO1
NM_144825.3 NP_659074.2 serine/threonine-protein kinase TAO1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in central nervous system neuron development IMP
IMP: Inferred from mutant phenotype
33565190 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase TAO1

  • serine/threonine protein kinase TAO1 homolog

  • thousand and one amino acid protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112136 TAO Kinase inhibitor 1 99.81% Unkown
HY-181280 VU6083859 Inhibitor 99.75% Unkown
HY-181281 VU6080195 Activator / Unkown
HY-RS14198 TAOK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-181619 TAO Kinase-IN-3 Inhibitor / Unkown
HY-RS18551 Taok1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25033 Taok1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Taok1 NCBI NCBI:57551