Tnfrsf18 - tumor necrosis factor receptor superfamily, member 18 Gene

Also Known as AITR; Gitr

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21936

Summary

Predicted to enable tumor necrosis factor-activated receptor activity. Involved in positive regulation of cell adhesion. Located in external side of plasma membrane. Is expressed in genitourinary system; gut; heart ventricle; lung; and skin. Orthologous to human TNFRSF18 (TNF Receptor Superfamily member 18). [provided by Alliance of Genome Resources, Apr 2022]

Tnfrsf18 Products (2)

mRNA Protein Name
NM_009400.3 NP_033426.1 tumor necrosis factor receptor superfamily member 18 isoform 1 precursor
NM_021985.3 NP_068820.1 tumor necrosis factor receptor superfamily member 18 isoform 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12478477 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of cell adhesion IMP
IMP: Inferred from mutant phenotype
23892569 MGI
Cellular Component GO Annotation Evidence References Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
16227984 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor necrosis factor receptor superfamily member 18

  • glucocorticoid-induced TNFR-related protein

Recombinant Tnfrsf18 Proteins

Cat. No. Product Name Accession Purity
HY-P72631 GITR Protein, Mouse (HEK293, Fc-His) O35714-1 (S22-H153) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P75164 GITR Protein, Mouse (HEK293, His) O35714-1/NP_033426.1 (S22-Q150) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P75165 GITR Protein, Mouse (HEK293, Fc) O35714 -1/NP_033426.1(Q20-H153) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14808 TNFRSF18 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17934 Tnfrsf18 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24404 Tnfrsf18 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991404 AMG-228 Inhibitor / Unkown
HY-P991464 IBI37G5 Inhibitor / Unkown
HY-P992354 FPA154 / Unkown
HY-P992395 JNJ-64164711 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfrsf18 NCBI NCBI:8784