Trhr - thyrotropin releasing hormone receptor Gene

Predicted to enable identical protein binding activity and thyrotropin-releasing hormone receptor activity. Predicted to be involved in Phospholipase C-activating G protein-coupled receptor signaling pathway; positive regulation of cytosolic calcium ion concentration; and positive regulation of protein-containing complex assembly. Predicted to act upstream of or within signal transduction. Predicted to be located in cell surface. Is expressed in several structures, including alimentary system; brain; heart; sensory organ; and skeleton. Used to study congenital hypothyroidism. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 7 and hypertension. Orthologous to human TRHR (thyrotropin releasing hormone receptor). [provided by Alliance of Genome Resources, Apr 2022]