Usf2 - upstream transcription factor 2 Gene

Also Known as Usf-2; bHLHb12

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22282

Summary

Enables DNA binding activity. Involved in lipid homeostasis and positive regulation of transcription from RNA polymerase II promoter by glucose. Acts upstream of or within lactation; positive regulation of transcription, DNA-templated; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; genitourinary system; and sensory organ. Orthologous to human USF2 (upstream transcription factor 2, c-Fos interacting). [provided by Alliance of Genome Resources, Apr 2022]

Usf2 Products (1)

mRNA Protein Name
NM_011680.2 NP_035810.1 upstream stimulatory factor 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
7523363 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
9890958 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
23749757 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular response to glucose stimulus IMP
IMP: Inferred from mutant phenotype
9890958 MGI
involved in glucose mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
9890958 MGI
acts upstream of or within lactation IMP
IMP: Inferred from mutant phenotype
12907752 MGI
involved in lipid homeostasis IMP
IMP: Inferred from mutant phenotype
9890958 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
15466854 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
9890958 MGI
involved in positive regulation of transcription from RNA polymerase II promoter by glucose IMP
IMP: Inferred from mutant phenotype
9890958 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
7523363 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
12907752 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

upstream stimulatory factor 2

  • major late transcription factor 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15514 USF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21454 Usf2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27972 Usf2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usf2 NCBI NCBI:7392