2. Gene
  3. MDN1 - midasin AAA ATPase 1 Gene

MDN1 - midasin AAA ATPase 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as Rea1

Gene ID: 23195 | Gene type: protein coding

About MDN1

Cytogenetic location: 6q15 Genomic coordinates (GRCh38): 6:89,642,498-89,819,794 (from NCBI)

This gene has 28 transcripts (splice variants), 1 gene allele, 209 orthologues and 3 paralogues. Ubiquitous expression in ovary (RPKM 5.6), testis (RPKM 4.9) and 25 other tissues.

Summary

Predicted to enable ATP binding activity. Involved in ribosomal large subunit assembly. Located in cytosol; intermediate filament cytoskeleton; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]

MDN1 Products(1)

mRNA Protein Name
NM_014611.3 NP_055426.1 midasin

MDN1 Protein Structure

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (325 - 452)

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (672 - 768)

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (816 - 902)

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (1079 - 1215)

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (1385 - 1540)

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (1749 - 1888)

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (2062 - 2106)

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (2219 - 2300)

  • 0
  • 900
  • 1800
  • 2700
  • 3600
  • 4500
  • 5596 a.a.
Protein Preferred Names Protein Names

midasin

MDN1, midasin homolog

Related Diseases

Diseases Alias
Acute Apical Periodontitis

Acute Apical Periodontitis Of Pulpal Origin

Acute Apical Periodontitis Nos

Aap - [Acute Apical Periodontitis]
Ewing Sarcoma Of Bone

Ewing'S Sarcoma Of Bone

Bone Ewing Sarcoma

Bone Ewing'S Sarcoma

Bone Localized Ewing Sarcoma

Bone Localized Ewing'S Sarcoma

Ewing'S Sarcoma/Bone Peripheral Primitive Neuroectodermal Tumor

Localized Skeletal Ewing'S Sarcoma

Localized Bone Ewing Sarcoma
Plasmodium Ovale Malaria

Ovale Malaria

Malariaby Plasmodium Ovale
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100816 Rbin-1 Inhibitor 99.33% Unkown
HY-100817 Rbin-2 ≥98.0% Unkown
HY-RS08268 MDN1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MDN1 MGD MGI:1926159
Macaca mulatta MDN1 VGNC VGNC:74530
Bos taurus MDN1 VGNC VGNC:31338
Canis familiaris MDN1 VGNC VGNC:43108
Rattus norvegicus MDN1 RGD RGD:1306394
Felis catus MDN1 VGNC VGNC:102458