A2m - alpha-2-macroglobulin Gene
Also Known as A2mp
Species: Mus musculus
Summary
Predicted to enable several functions, including cytokine binding activity; growth factor binding activity; and serine-type endopeptidase inhibitor activity. Acts upstream of or within stem cell differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; embryo mesenchyme; liver; meninges; and retina. Human ortholog(s) of this gene implicated in COVID-19; background diabetic retinopathy; multiple sclerosis; neurodegenerative disease (multiple); and obstructive lung disease. Orthologous to human A2M (alpha-2-macroglobulin). [provided by Alliance of Genome Resources, Apr 2022]
A2m Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_175628.3 | NP_783327.2 | alpha-2-macroglobulin-P precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
17920016 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within stem cell differentiation |
IDA
IDA: Inferred from direct assay
|
19796622 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
alpha-2-macroglobulin-P |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS00010 | A2M Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-CE00893 | 2M2PE-CoA | / | Unkown | |
| HY-RS18322 | A2m Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS19112 | Pzp Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS24800 | A2m Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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