P2ry6 - pyrimidinergic receptor P2Y, G-protein coupled, 6 Gene

Also Known as P2Y6; 2010204J23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 233571

About P2ry6

Chromosome 7: 100,586,837-100,623,856 reverse strand.GRCm39:CM001000.3

This gene has 3 transcripts (splice variants), 183 orthologues, 13 paralogues and is associated with 3 phenotypes. Broad expression in colon adult (RPKM 37.), lung adult (RPKM 23.5) and 16 other tissues.

Summary

Enables G protein-coupled UDP receptor activity. Acts upstream of or within cellular response to organic cyclic compound; cellular response to prostaglandin E stimulus; and transepithelial chloride transport. Predicted to be located in apical plasma membrane and basolateral plasma membrane. Is expressed in dermomyotome and musculature. Orthologous to human P2RY6 (pyrimidinergic receptor P2Y6). [provided by Alliance of Genome Resources, Apr 2022]

P2ry6 Products (1)

mRNA Protein Name
NM_183168.2 NP_898991.1 P2Y purinoceptor 6

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables G protein-coupled UDP receptor activity IDA
IDA: Inferred from direct assay
11259526 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to organic cyclic compound IDA
IDA: Inferred from direct assay
23479225 MGI
acts upstream of or within cellular response to prostaglandin E stimulus IDA
IDA: Inferred from direct assay
23479225 MGI
acts upstream of or within transepithelial chloride transport IDA
IDA: Inferred from direct assay
11259526 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

P2ry6 Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (26 - 311)

7tm_GPCRs

7tm_GPCRs: cd14964 (28 - 52)

7tm_GPCRs

7tm_GPCRs: cd14964 (61 - 82)

7tm_GPCRs

7tm_GPCRs: cd14964 (99 - 121)

7tm_GPCRs

7tm_GPCRs: cd14964 (145 - 161)

7tm_GPCRs

7tm_GPCRs: cd14964 (189 - 212)

7tm_GPCRs

7tm_GPCRs: cd14964 (237 - 259)

7tm_GPCRs

7tm_GPCRs: cd14964 (279 - 304)

  • 0
  • 100
  • 200
  • 300
  • 328 a.a.
Protein Preferred Names Protein Names

P2Y purinoceptor 6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09934 P2RY6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-117356A MRS2693 ammonium / Unkown
HY-RS09935 P2ry6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09936 P2ry6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens P2ry6 NCBI NCBI:5031