CLEC5A - C-type lectin domain containing 5A Gene

Homo sapiens

Also known as MDL1; MDL-1; CLECSF5

Gene ID: 23601 | Gene type: protein coding

About CLEC5A

Cytogenetic location: 7q34 Genomic coordinates (GRCh38): 7:141,927,357-141,946,974 (from NCBI)

This gene has 7 transcripts (splice variants), 224 orthologues and 23 paralogues. Biased expression in bone marrow (RPKM 12.6), appendix (RPKM 4.1) and 6 other tissues.

Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined. [provided by RefSeq, Jul 2008]

CLEC5A Products(2)

mRNA	Protein	Name
NM_001301167.2	NP_001288096.1	C-type lectin domain family 5 member A isoform 2
NM_013252.3	NP_037384.1	C-type lectin domain family 5 member A isoform 1

CLEC5A Protein Structure

Lectin_C

0
100
188 a.a.

Protein Preferred Names

Protein Names

C-type lectin domain family 5 member A

C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5

Recombinant CLEC5A Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77632	CLEC5A/MDL-1 Protein, Human (HEK293, Fc)	Q9NY25 (Y26-K188)	≥95%

Related Diseases

Diseases

Alias

Dengue Virus

Dengue Virus, Susceptibility To	Dengue Fever, Protection Against
Dengue Fever

Dengue Hemorrhagic Fever

Severe Dengue	Dengue Haemorrhagic Fever
Dhf	Severe Dengue Haemorrhagic Fever
Severe Dengue Fever	Dengue Shock Syndrome

Dengue Shock Syndrome

Dss

Dengue Disease

Dengue Fever	Dengue
Df	Dengue Shock Syndrome
Dengue Virus Infection	Breakbone Fever
Classic Dengue	Classical Dengue
Dengue Hemorrhagic Fever	Hemorrhagic Dengue
Philippine Hemorrhagic Fever	Singapore Hemorrhagic Fever
Thai Hemorrhagic Fever	Severe Dengue
Dengue Fever Without Warning Signs	Dengue Haemorrhagic Fever Grade 1
Dengue Haemorrhagic Fever Without Warning Signs	Bangkok Haemorrhagic Fever
Singapore Haemorrhagic Fever	Thailand Haemorrhagic Fever
Southeast Asia Haemorrhagic Fever	Dhf -[Dengue Haemorrhagic Fever]
Dengue Fever With Warning Signs	Dengue Haemorrhagic Fever With Warning Signs
Dengue Haemorrhagic Fever Grade 2	Philippine Haemorrhagic Fever

Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy 1

Nasu-Hakola Disease	Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy
Plosl	Nhd
Presenile Dementia With Bone Cysts	Plo-Sl
PLOSL1	Dementia, Prefrontal, With Bone Cysts
Dementia, Progressive, With Lipomembranous Polycystic Osteodysplasia	Brain-Bone-Fat Disease
Progressive Dementia With Lipomembranous Polycystic Osteodysplasia	Brain-Bone-Fat Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02798	CLEC5A Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CLEC5A	VGNC	VGNC:39334
Felis catus	CLEC5A	VGNC	VGNC:60954
Mus musculus	CLEC5A	MGD	MGI:1345151
Rattus norvegicus	CLEC5A	RGD	RGD:1584755
Bos taurus	CLEC5A	VGNC	VGNC:27435
Macaca mulatta	CLEC5A	VGNC	VGNC:71252
Others	CLEC5A	NCBI

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