CLEC5A Antibody (YA4532)
(Synonyms: MDL1; MDL-1; CLECSF5)CLEC5A Antibody (YA4532) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CLEC5A.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:400 | 1:10000 |
Product Details
CLEC5A Antibody (YA4532) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CLEC5A.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 30-40 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 22 kDa
Purified recombinant fragment of human CLEC5A (AA: extra(28-188)) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CLEC5A receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differentiation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface
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Subcellular Localization
Secreted; Cell membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:One or more isoforms were found in the myeloid leukemia cell line KG-1, the leukemia U-937 cell line, bone marrow cells, placenta, and peripheral blood granulocytes. The isoform GCSFR-2 was present only in leukemia U-937 cells. The isoform GCSFR-3 was highly expressed in the placenta. -
Isoforms & Post-Translational Modification
Q99062 has 4 isomers: Q99062-1: 92156 Da (predicted); Q99062-2: 85120 Da (predicted); Q99062-3: 95114 Da (predicted); Q99062-4: 86609 Da (predicted).
N-glycosylated -
Subunit
Homodimer. The dimeric receptor binds two CSF3 molecules.
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SwissProt ID
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Synonyms
MDL1; MDL-1; CLECSF5
Documentation
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