Def6 - differentially expressed in FDCP 6 Gene

Also Known as Ibp; Slat; Slat2; Slat6; 2410003F05Rik; 6430538D02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23853

Summary

Located in cell-cell junction. Is expressed in several structures, including heart; hemolymphoid system; lung; metanephros; and musculature. Used to study systemic lupus erythematosus. Orthologous to human DEF6 (DEF6 guanine nucleotide exchange factor). [provided by Alliance of Genome Resources, Apr 2022]

Def6 Products (1)

mRNA Protein Name
NM_027185.3 NP_081461.2 differentially expressed in FDCP 6

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17403664 MGI
Cellular Component GO Annotation Evidence References Source
located in cell-cell junction IDA
IDA: Inferred from direct assay
23793062 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

differentially expressed in FDCP 6

  • DEF-6

  • IRF-4-binding protein

  • IRF4-binding protein

  • SWAP-70-like adapter of T-cells

Def6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Def6 Q8C2K1 Itga7 Mus musculus Q61738-6
IF
17403664
Intra
Def6 Q8C2K1 Itga7 Mus musculus Q61738-6
Y2H
17403664
Intra
Def6 Q8C2K1 Itga7 Mus musculus Q61738-6
Anti Tag CoIP
17403664
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-23970 4,4'-(5,6,12,13-Tetrachloro-1,3,8,10-tetraoxo-1,3,8,10-tetrahydroanthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-2,9-diyl)dibenzoic acid 95.0% Unkown
HY-RS21321 Def6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03671 DEF6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03677 DEFA6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W075595 (2S,2'S)-2,2'-(1,3,8,10-Tetraoxo-1,3,8,10-tetrahydroanthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-2,9-diyl)dipropionic acid / Unkown
HY-W1049785 5,6,12,13-Tetrakis(4-(tert-butyl)phenoxy)-2,9-di(pyridin-4-yl)anthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetraone / Unkown
HY-W112588 2,9-Di(pyridin-4-yl)anthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetraone / Unkown
HY-W856222 5,5'-(1,3,8,10-Tetraoxo-1,3,8,10-tetrahydroanthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-2,9-diyl)diisophthalic acid / Unkown
HY-RS27840 Def6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Def6 NCBI NCBI:50619