Avp - arginine vasopressin Gene

Also Known as DI; VP; ADH; Vas

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24221

Summary

Enables V1A Vasopressin Receptor binding activity; V1B Vasopressin Receptor binding activity; and neuropeptide hormone activity. Involved in several processes, including cellular cation homeostasis; mating; and regulation of secretion. Located in dendrite; extracellular space; and secretory granule. Used to study diabetes insipidus; hyperglycemia; portal hypertension; temporal lobe epilepsy; and type 1 diabetes mellitus. Biomarker of hypertension; neurohypophyseal diabetes insipidus; type 2 diabetes mellitus; and vascular dementia. Human ortholog(s) of this gene implicated in diabetes insipidus and neurohypophyseal diabetes insipidus. Orthologous to human AVP (arginine vasopressin). [provided by Alliance of Genome Resources, Apr 2022]

Avp Products (1)

mRNA Protein Name
NM_016992.2 NP_058688.2 vasopressin-neurophysin 2-copeptin preproprotein
Protein Preferred Names Protein Names

vasopressin-neurophysin 2-copeptin

  • AVP-NPII

  • antidiuretic hormone

  • arginine vasopressin (Diabetes insipidus), same as Di (conflicting physical mapping)

  • prepropressophysin

  • preprovasopressin-neurophysin

  • vasopressin

  • vasopressin-neurophysin prepropeptide

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-17000 Tolvaptan 99.95% Yes
HY-B1811 Vasopressin 99.65% Yes
HY-P0049 Argipressin Agonist 98.71% Unkown
HY-18346 Mozavaptan Antagonist 99.71% Unkown
HY-123593 Mozavaptan hydrochloride Antagonist 99.80% Unkown
HY-P0049A Argipressin diacetate / Unkown

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-10066 Nelivaptan Antagonist 99.89% Phase 2
HY-133173 Niravoline Agonist / Phase 2
HY-19070 BRL-52656 Agonist / Phase 1

Pre-clinical Phase

Bioactive Molecules (28)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-103023 CLP290 Activator 99.96% Unkown
HY-P1390 d[Cha4]-AVP Agonist 98.81% Unkown
HY-W539944 Argipressin acetate 99.16% Unkown
HY-RS09357 NLRP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-103703 DEAE Cross-linked dextran A 25 / Unkown
HY-134454A Z-Pro-prolinal Inhibitor 99.9% Unkown
HY-157220 Tolvaptan phosphate ester sodium Antagonist 99.85% Unkown
HY-P3066 SKF 100398 99.48% Unkown
HY-P4990 Pro8-Oxytocin Activator 99.68% Unkown
HY-P4990A Pro8-Oxytocin TFA Activator 99.68% Unkown
HY-RS06579 IFNAR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-118768 FMS586 free base / Unkown
HY-165484 AVP-13358 Inhibitor / Unkown
HY-18346S Mozavaptan-d6 Antagonist / Unkown
HY-P10046 [Deamino-Pen1,Val4,D-Arg8]-vasopressin Inhibitor / Unkown
HY-P1390A d[Cha4]-AVP TFA Agonist / Unkown
HY-P1747 Pneumadin, rat / Unkown
HY-P4010 Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin Agonist / Unkown
HY-P5007 Copeptin (human) / Unkown
HY-RS01280 AVP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W583271 Zn(II) Deuteroporphyrin IX 2,4 bis ethylene glycol Inhibitor / Unkown
HY-111291 ICI 169369 free base Inhibitor / Unkown
HY-118918 YM218 free base Antagonist / Unkown
HY-129333 L-364918 Antagonist / Unkown
HY-17000S Tolvaptan-d7 / Unkown
HY-P5006 (d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin Antagonist / Unkown
HY-RS16746 Avp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23183 Avp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Avp NCBI NCBI:551