Hcar1 - hydrocarboxylic acid receptor 1 Gene

Also Known as Gpr81

Species: Mus musculus

Gene Type: protein coding
Gene ID: 243270

Summary

Enables G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway and negative regulation of lipid catabolic process. Is active in membrane. Orthologous to human HCAR1 (hydroxycarboxylic acid receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Hcar1 Products (1)

mRNA Protein Name
NM_175520.5 NP_780729.3 hydroxycarboxylic acid receptor 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables G protein-coupled receptor activity IDA
IDA: Inferred from direct assay
19047060 MGI
Biological Process GO Annotation Evidence References Source
involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
19047060 MGI
involved in negative regulation of lipid catabolic process IDA
IDA: Inferred from direct assay
19047060 MGI
Cellular Component GO Annotation Evidence References Source
is active in membrane IDA
IDA: Inferred from direct assay
19047060 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hydroxycarboxylic acid receptor 1

  • G-protein coupled receptor 81

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B2227B Lactic acid sodium (60% w/w in water) Activator 98.0% Unkown
HY-B2227 Lactic acid Activator / Unkown
HY-B2227A Lactic acid calcium Activator 98.5% Yes

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W016868 3-Chloro-5-hydroxybenzoic acid Agonist 99.54% Unkown
HY-W015560 3,5-Dihydroxybenzoic acid Agonist 99.98% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hcar1 NCBI NCBI:27198